An experiment entitled “Impact of herbicide application on yield and economics of chickpea (Cicer arietinum L.)” was conducted during rabi 2021 at Agronomy Research Farm, Agronomy Department, College of Agriculture, Dhule. The experiment was comprised of ten treatments laid out in a randomized block design with three replications. Among the different herbicide application treatments, grain and straw yield was observed to be higher with the application of the pre-emergence herbicide of oxyfluorfen 0.1 kg a.i. ha-1 fb tank mix imazethapyr (50% a.i.) + quizalofop ethyl (50% a.i.) (PoE) (T10), and it was found to be at par with the application of pendimethalin 1 kg a.i. ha-1 (PE) fb tank mix imazethapyr (50% a.i.) + quizalofop ethyl (50% a.i.) (PoE) (T7), pendimethalin 1 kg a.i. ha-1 at PE fb one hand weeding (T3), and oxyfluorfen 0.1 kg a.i. ha-1 at PE fb one hand weeding (T4). Higher gross returns, net monetary returns, and B:C ratio was in the treatment with the application of the pre-emergence herbicide of oxyfluorfen 0.1 kg a.i. ha-1 fb tank mix imazethapyr (50% a.i.) + quizalofop ethyl (50% a.i.) (PoE) among the different herbicide application treatments.