A field experiment was conducted during the kharif season 2023, at the Crop Research Farm, Department of Agronomy, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology and Sciences. To determine “Influence of biofertilizers and boron on growth and yield of cowpea”. The treatments consisted of seed treatment with Rhizobium (20g/kg seed), PSB (Phosphate Solubilising Bacteria) 20g/kg seed and three levels of boron (1, 2 and 3 kg/ha). The experiment was laid out in a Randomized Block Design with 10 treatments and replicated thrice. The results revealed that significantly higher plant height (cm) (46.10), maximum number of nodules/plant (21.94), higher plant dry weight (57.05g), higher crop growth rate (17.23 g/m2/day), higher relative growth rate(0.0230 g/g/day), maximum number of pods/plant (14.78), maximum number of seeds/pod (10.57), higher test weight (g) (27.50), higher grain yield (5207.48 kg/ha), higher Stover yield (7000.00 kg/ha) higher harvest index (42.66%) were recorded in treatment 9 (Rhizobium + PSB + Boron 3kg/ha). The maximum gross return, net return and benefit cost ratio were also recorded with application of Rhizobium + PSB + Boron 3 kg/ha (treatment 9) was found to be productive as well as economically feasible.