The experiment was conducted at Instructional cum research Farm, Indira Gandhi Agriculture University, Raipur (C.G.) during Kharif 2018 to study effect of de-topping and nitrogen levels on yield and nutrients uptake of maize (Zea mays L.) with two maize varieties (African tall and hybrid 25K55). The trial was conducted in split plot design with three replication in which de-topping and no de-topping were taken in main plot and four nitrogen levels in sub plot. The results of experiment maximum green fodder yield from de-topped portion (86.09 qha-1) was observed in D2N4 de-topping in African tall along with 150 kg N ha-1. Whereas the nutrient uptake was maximum in D3N4 Hybrid 25K55 with no-detopping in grains and maximum nutrient uptake in stover was obtained in D1N4 no de-topping in African tall with 150 kg N ha-1. when practiced de-topping.